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Found 10 results

  1. An interesting study I'd not seen before now, thank you to Don Shadow for bringing this to my attention. I thought it may be of interest to others and so worthy of sharing. Study: Matshushima, Y., Shirota, O., Kikura-Hanajiri, R., Gosa, Y. & Eguchi, F. et al. (2009) Effects of Psilocybe argentipes on Marble-Burying Behaviour in Mice. Bioscience, Biotechnology, and Biochemistry, 73,8: 1866-8. https://pdfs.semanticscholar.org/27db/ba7610194971742f8adf5a8dde8e3b06addb.pdf?fbclid=IwAR2ld6CQCuz3ax1mDPe4qO8sstDrMyrrS92AUiUy6eN4u7tEmIX0r5mvkBQ Abstract Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy. ...we obviously need to be cautious when attempting to extrapolate and infer from animal model studies (in this case an animal model of OCD), but I thought this was quite an interesting finding: "In the experiments, when mice consumed P. subcaerulipes, it significantly inhibited their marble-burying behavior, but, unlike an equivalent dose of purified psilocybin, did not affect locomotor activity. Further, the mushroom was more effective than purified psilocybin in inhibiting the behavior, and lower doses were required. Based on these results, the authors suggest that the mushroom has the potential "to be efficient in clinical obsessive-compulsive disorder therapy". This is at the very least suggestive that there could be secondary compounds in the mushroom that modulate or synergise with the psilocybin in mushrooms to some degree, beneficially in this case (even if it is the presence of psilocybin/serotonin precursors in the mushroom) and these compounds may be lacking when ingesting pure synthetic psilocybin. Much of the psilocybin mushroom potency data is out of date, and more research on the potential modulating influence of secondary compounds found in mushrooms (such as baeocystin/norbaeocystin and others) is certainly warranted.
  2. Skin Absorption?

    Hey I have a weird question: Do any of you know if psilocybin from powdered mushrooms is absorbed through the skin or lungs? I am grinding up most of my mushrooms into a powder for encapsulation. The resulting powder is very fine, kind of like powdered sugar, only lighter. While doing that the air can get an occasional cloud of psilocybin mushroom dust, and my fingers tend to get covered in powder. I hadn't really thought much about this but after making 300 capsules the other day my finger tips appeared to be "happy" -- just a little tickly feeling as I handled the individual capsules.
  3. Having so much fun growing, I want to try growing some gold and pink oyster mushrooms. To be very generally, I typically do a G2G transfer bulk grow for my cubes. Does this same technique work for oyster mushrooms? I know some mushrooms need very specific grow methods, ie. Chanterelles need to be near the roots of certain trees. Info about any other edible mushrooms would be great too! I just have a source for oyster mushroom spores. As always, mush appreciated!
  4. Time to go big

    Well I've gotten pretty comfortable with cakes and growing the shrooms, I've had a couple ounces now between the last couple batches. It's not quite as much as I expected and it's all been from MS as well. I'm looking to move forward and get into bulk growing with hgher quality spores. I also would like to get into using spore prints, but I have no idea how to use them or make liquid culture, none of that. All I know is the cake stuff. I was wondering what my next step should be. Which shrooms to buy? What materials? Which tek is the easiest for a novice like myself to start with? Some advice would be useful, I'd appreciate it.
  5. Golden Teachers, Midwest grow kit, 3 lbs Rye berries, 5lbs Midwest select bulk casing mix (layered) 9 day of colonization (last 36hrs covered with wax paper to start pinning, no pins). Should I wait for the pinning to start under the wax paper or should I start fruiting? and why does it look like crystals?
  6. Shrooms and absinthe

    So everything I see says to not mix shroom and alcohol, yet the best trip ive ever had was when I mixed a 3.5 gram dose with a half-pint of absinthe, and a hearty helping of moonshine cherries. Has anyone else had experience mixing psilocybin with absinthe?
  7. Whilst picking away at my first albeit poor ztub crop I pondered possible preferable pharmacons for a pleasant preparation of pins and primordia for personal pleasure. All alliterations aside, these tiny little buddies are all dirty with casing, as you all know. So I was thinking I could use the lemon tek or a tea tek and strain through a coffee filter, then I thought of these jars of lactic acid I have sitting around. I googled this and only found information about using lactic acid bacteria in mushroom production. Didn't really read that yet. Has anybody ever tried extracting compounds from shrroomies with Lactic acid? Any chemists out there? If nobody answers I'll probably just try it anyway... Peace!
  8. I am a new member of Shroomology... Hoping to find ways to tap into the new psychedelic underground, for selfish reasons I must admit. I am conducting research on profound experiences while taking psilocybin. I have a short questionnaire, it is anonymous, and participation is greatly appreciated. Thanks Shroomology, so many great resources on the site. The Survey
  9. Hi peeps, Out of pure curiousity, I'm wondering how many of you guys have entity encounters on psilocybin, or contact with that what you would consider "other" in some way?? Entity encounters are commonly reported with DMT and psilocybin...I've not yet has such an experience on DMT, and only a single entity encounter so far which was amazing...this came about through a combo of Syrian rue extract and 10g of fresh Hawaiian Pan cyans. During the experience, out of a chaotic mess of patterns and fractals emerged this octopus, shimmering bioluminescent, electric blue, and it was studying me it seemed, peering at me with one eye as I later found out they do, while crawling upwards on the other side of the room. It then spurted out some colourful fractals at me, like they do with ink, almost like it was trying to communicate, before dissolving back from whence it came. It was a strange experience in that I had not been thinking about octopi at the time, although I do think they are amazing things, and it was bizarre to have that feeling of being watched and studied by something during what was my trip! The closest earthy reflection of what I saw was something like the blue ringed octopus, pictured. Has anyone else had encounters with entities or presences while bemushroomed?? If so, I'd like to hear about it!
  10. All active Psilocybe mushrooms contain the same main substances which are psilocybin, psilocin and to a lesser degree baeocystin and norbaeocystin. The amounts and proportions of those 4 key components varies among different species and strains. Alongside with those 4 main components there are many other substances, which by them self don't have a described psychoactive effect, but might very well have a slight modifying effect on the psychoactive properties of the key components.Another likely cause for the different effect of different mushrooms is the influence of the effect of stomach contents, MOIA inhibitors, and set and setting on the psychedelic experience.The use of any hallucinogen involves "set," i.e. mind-set, mood, emotional state and "setting," the environment and/or people with whom one is tripping at the time. The combination of set and setting in conjunction with the effects of the drug produce the kind of trip one has, good or bad. People can and do experience psychotic breaks from reality in a "bad" trip and this can be extremely traumatic with long-term and lingering after effects. A good trip can be very euphoric and transcendent in comparison. Which you’ll get is again, dependent on set, setting, the drug and certain amount of luck and randomness.
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